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Invitrogen™ Human HTRA3 (aa 337-449) Control Fragment Recombinant Protein

Catalog No. RP91877
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RP91877 100 μL
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Catalog No. RP91877 Supplier Invitrogen™ Supplier No. RP91877
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-110869. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

HtrA3 belongs to the human high-temperature requirement factor A (HtrA) family. It is also called pregnancy-related serine protease. HtrA3 has two isoforms (long and short), which is produced by alternative splicing. Similar to HtrA1, HtrA3 binds to various TGF-beta proteins and inhibited the signaling of BMP-4, -2 and TGF-beta 1. HtrA3 does not inhibit signaling originated from a constitutively active BMP receptor, indicating that the inhibition occurred upstream of the cell surface receptor.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P83110
Concentration ≥5.0 mg/mL
For Use With (Application) Neutralization, Control
Formulation PBS, 1M urea with no preservative; pH 7.4
Gene ID (Entrez) 94031
Name Human HTRA3 (aa 337-449) Control Fragment
pH Range 7.4
Purification Method Purified
Quantity 100 μL
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias 2210021K23Rik; 9530081K03Rik; High-temperature requirement factor A3; HtrA serine peptidase 3; Htra3; Pregnancy-related serine protease; probable serine protease HTRA3; Prsp; RGD1308120; Serine protease HTRA3; Tasp; Toll-associated serine protease
Common Name HTRA3
Gene Symbol HTRA3
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence ITRFLTEFQDKQIKDWKKRFIGIRMRTITPSLVDELKASNPDFPEVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEAVLTESPLLLEVRRGNDDLLFSIAP
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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