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Gibco™ Human IFN-alpha A/D Recombinant Protein

Catalog No. PHC4044
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Recombinant Protein

Carrier-Free Dilution Recommendation: Further dilutions should be made in medium or buffered solution containing carrier protein such as PBS with 0.1% BSA.

Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P01562, P05014
For Use With (Application) Bioactivity
Formulation PBS with 0.1% BSA and no preservative
Gene ID (Entrez) 3439, 3441
Molecular Weight (g/mol) 19.4 kDa
Name Human IFN-alpha A/D
Purification Method Purified
Quantity 1 x 10^5 units
Storage Requirements -80°C
Regulatory Status RUO
Gene Alias IFL; IFN; IFNA@; IFNA1; IFNA13; IFNA4; IFN-ALPHA; IFN-alpha 1b; IFN-alpha-1/13; IFN-alpha-4; IFN-alpha4a; IFN-alphaD; INFA4; Interferon; interferon alpha 1; interferon alpha 1b; interferon alpha 4; Interferon alpha-1; interferon alpha-1/13; Interferon alpha-4; interferon alpha-4B; Interferon alpha-76; interferon alpha-D; Interferon alpha-M1; interferon, alpha 1; interferon, alpha 4; interferon-alpha1; leIF D
Common Name IFN alpha A/D
Gene Symbol IFNA1, IFNA4
Biological Activity Specific Activity = 1.8 x 10e8 units/mg; Assay used to measure bioactivity: Interferon was titrated with the use of the cytopathic effect inhibition assay as described by Rubinstein, et al. In this antiviral assay for interferon about 1 unit/mL of interferon is the quantity necessary to produce a 50% cytopathic effect. The units are determined with respect to the international reference standard for human interferon alpha A (Hu-IFN-αA) provided by the National Institutes of Health. The units of activity are determined with bovine MDBK cells infected with vesicular stomatitis virus (VSV).
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Content And Storage -80°C
Activity Specific Activity = 1.8x10e8 units/mg; Assay used to measure bioactivity: Interferon was titrated with the use of the cytopathic effect inhibition assay as described by Rubinstein, et al. In this antiviral assay for interferon about 1 unit/mL of interferon is the quantity necessary to produce a 50% cytopathic effect. The units are determined with respect to the international reference standard for human interferon alpha A (Hu-IFN-αA) provided by the National Institutes of Health. The units of activity are determined with bovine MDBK cells infected with vesicular stomatitis virus (VSV).
Shipping Condition Dry Ice
Expression System E. coli
Protein Family Cytokines & Receptors
Protein Form Recombinant, Ligand
Form Liquid
Protein Subtype Interferons
Research Category Immunology, Virology, Oncology, Signal Transduction
Product Line Gibco
Purity or Quality Grade >95%
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