Invitrogen™ Human IFN-omega Recombinant Protein

Catalog No.	Quantity
PI113951	25 μg

Catalog No. PI113951 Supplier Invitrogen™ Supplier No. 113951

Description

Recombinant Protein

Store at -20°C or below for retention of full activity. Thaw product vial by incubation in cold tap water until just thawed. Aliquot and refreeze unused contents to minimize effects of freeze thawing. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of product should be in buffers containing protein such as 0.1% BSA or tissue culture media with serum.

IFN-omega is a type I interferon that can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-alpha, IFN-beta, and IFN-omega, signal through the IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities. IFN-omega exhibits about 75% sequence homology with IFN-alpha, and contains two conserved disulfide bonds that are necessary for full biological activity.

Specifications

• Accession Number: P05000
• Concentration: Lot-specific
• For Use With (Application): ELISA, Immunoprecipitation, Western Blot
• Formulation: PBS with 2% BSA and no preservative
• Gene ID (Entrez): 3467
• Molecular Weight (g/mol): 20 kDa
• Name: Human IFN-omega
• Quantity: 25 μg
• Source: E. Coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: IFN o; IFN ?; IFNo; IFNomega; IFN-omega 1, interferon omega-1; IFNW; IFNW1; IFN?; Interferon; Interferon alpha-II-1; Interferon o; Interferon OMEGA; interferon omega 1; interferon omega-1; Interferon ?; interferon, omega 1
• Common Name: IFN omega
• Gene Symbol: IFNW1
• Biological Activity: EC50 ̃ 1 U/mL; determined by use of the cytopathic effect inhibition assay described in [Rubinstein, S. et al. (1981). J. Virol. 37, 755-758 ]; [Familletti, P.C. et al. (1981). Methods in Enzymology, Vol. 78, 387-394 ]. The units are determined with respect to the international reference standard for human interferon alpha A (Hu-IFN-alpha-A) provided by the National Institutes of Health [see Pestka, S. (1986). Methods in Enzymology, Academic Press, New York 119, 14-23 ]. Unit of activity measured on bovine MDBK cells with vesicular stomatitis virus (VSV).SV).
• Conjugate: Unconjugated
• Species: E. coli
• Recombinant: Recombinant
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Protein Subtype: Recombinant
• Purity or Quality Grade: >95%