Invitrogen™ Human IFN-omega Recombinant Protein

Catalog No.	Quantity
50-924-6	25 μg

Catalog No. 50-924-6 Supplier Invitrogen™ Supplier No. BMS304

Description

Recombinant Protein

Description: In the human genome, the IFN-omega gene family consists of seven members located on chromosome 9. However, only one of these genes is functional giving rise to the IFN-omega protein, whereas the others are non-functional pseudogenes. The IFN-omega gene is not expressed in unstimulated cells. Viral infection results in expression of the gene giving rise to the N-glycosylated protein consisting of 172 or 174 amino acids and an apparent molecular mass of about 25kDa. A single carbohydrate group consists mainly of biantennary complex oligosaccharides with variable amounts of N-acetyl neuraminic acid. In quantitative terms, IFN-omega is a major component of human leukocyte IFN; with a contribution to its total antiviral activity estimated to be in the range of 10 -15 %. Purity: >95% prior to addition of human serum albumin. Molecular Weight: 20.0 kDa.

IFN-omega is a type I interferon that can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-alpha, IFN-beta, and IFN-omega, signal through the IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities. IFN-omega exhibits about 75% sequence homology with IFN-alpha, and contains two conserved disulfide bonds that are necessary for full biological activity.

Specifications

• Accession Number: P05000
• Concentration: 50 μg/mL
• For Use With (Application): Neutralization, ELISA Standard
• Formulation: PBS with 20mg/mL BSA and no preservative
• Gene ID (Entrez): 3467
• Molecular Weight (g/mol): 20 kDa
• Name: Human IFN-omega
• Purification Method: Purified
• Quantity: 25 μg
• Source: E. coli
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: IFN o; IFN ω; IFNo; IFNomega; IFN-omega 1, interferon omega-1; IFNW; IFNW1; IFNω; Interferon; Interferon alpha-II-1; Interferon o; Interferon OMEGA; interferon omega 1; interferon omega-1; Interferon ω; interferon, omega 1
• Common Name: IFN omega
• Gene Symbol: IFNW1
• Product Type: Protein
• Conjugate: Unconjugated
• Species: E. coli
• Recombinant: Recombinant
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Protein Subtype: Recombinant
• Purity or Quality Grade: >95% prior to addition of human serum albumin

Safety and Handling

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