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ABclonal Technology Human IgM FC Rabbit mAb
SDP

Catalog No. 5000013173
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Immunoglobulins (Ig) are antigen recognition molecules of B cells composed of 2 identical heavy chains and 2 identical light chains linked by disulfide bonds Each heavy chain has a variable (V) region for antigen binding and a constant (C) region that defines the isotype and provides effector functions The V region is encoded by V J and D genes while C region genes are clustered on chromosome 14 The IGHM gene encodes the C region of the mu heavy chain defining the IgM isotype Naive B cells express transmembrane IgM and IgD Activated B cells can switch to different heavy chain isotypes via somatic recombination Secreted Ig forms such as IgM are produced through alternative RNA processing and typically exist as pentamers or hexamers in plasma

Catalog No. 50-000-13173 Supplier ABclonal Technology Supplier No. A24260100UL
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Immunoglobulins (Ig) are antigen recognition molecules of B cells composed of 2 identical heavy chains and 2 identical light chains linked by disulfide bonds Each heavy chain has a variable (V) region for antigen binding and a constant (C) region that defines the isotype and provides effector functions The V region is encoded by V J and D genes while C region genes are clustered on chromosome 14 The IGHM gene encodes the C region of the mu heavy chain defining the IgM isotype Naive B cells express transmembrane IgM and IgD Activated B cells can switch to different heavy chain isotypes via somatic recombination Secreted Ig forms such as IgM are produced through alternative RNA processing and typically exist as pentamers or hexamers in plasma

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