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CPC Scientific H-Leu-Lys-Lys-Glu-Arg-Leu-Leu-Asp-Asp-Arg-His-Asp-Ser-Gly-Leu-Asp-Ser-Met-Lys-Asp-OH (trifluoroacetate salt) 1MG
Supplier: CPC Scientific SIGN007A
This peptide is a 20 to 39 amino acid residues fragment of human IkBa,. Following cellular stimulation, specific IkB kinases (IKKs) are activated resulting in phosphorylation of serines 32 and 36 on human IkBa. The subsequent cascade of cellular events leads to the translocation of transcription factor to the nucleous where it initiates specific transcription. ONE-LETTER SEQUENCE: LKKERLLDDRHDSGLDSMKDMOLECULAR FORMULA: C125H189N33O41S2MOLECULAR WEIGHT:2371.7STORAGE CONDITIONS: -20 5CRESEARCH AREA: Protein Kinases and PhosphatasesREFERENCES: Ciechanover, A. et al. Biochimie 83, 341 (2001).
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