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Gibco™ Human IL-19 Recombinant Protein, PeproTech®

Catalog No. p-7245978
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Catalog No. Quantity
20019100UG 100 μg
200-19-10UG 10 μg
200-19-1MG 1 mg
20019250UG 250 μg
200-19-2UG 2 μg
20019500UG 500 μg
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Catalog No. 20019100UG Supplier Gibco™ Supplier No. 20019100UG
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Description

Recombinant Protein

Recombinant Human IL-19 is a 35.8 kDa homodimer of two 154 amino acid chains. In solution, IL-19 exists predominantly as a non-disulfide-linked dimer. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9UHD0
For Use With (Application) ELISA, Functional Assay, Western Blot
Formulation protein with no preservative
Gene ID (Entrez) 29949
Molecular Weight (g/mol) 35.8 kDa
Name Human IL-19
Quantity 100 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias il 19; IL-10 C; IL19; IL-19; ILN; Interleukin; interleukin 19; Interleukin19; interleukin-19; MDA1; MDA-1; melanoma differentiation associated protein-like protein; melanoma differentiation-associated protein-like protein; NG0.1; ZMDA1
Common Name IL-19
Gene Symbol IL19
Biological Activity Determined by its ability to stimulate the proliferation of HEK-Blue IL-19 TM reporter cells.
Conjugate Unconjugated
Recombinant Recombinant
Sequence MLRRCLISTD MHHIEESFQE IKRAIQAKDT FPNVTILSTL ETLQIIKPLD VCCVTKNLLA FYVDRVFKDH QEPNPKILRK ISSIANSFLY MQKTLRQCQE QRQCHCRQEA TNATRVIHDN YDQLEVHAAA IKSLGELDVF LAWINKNHEV MSSA
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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