Invitrogen™ Human IL-23 R ELISA Kit

Catalog No.	Quantity
EH268RBX5	5 x 96 Tests
EH268RB	96 Tests

Catalog No. EH268RBX5 Supplier Invitrogen™ Supplier No. EH268RBX5

Description

ELISA

Human IL-23 R quantitates human IL-23 R in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-23 R.

IL-23R is a 629 aa, novel subunit of the receptor for cytokine IL23A/IL23 which pairs with the receptor molecule IL12RB1/IL12R beta 1and thus take part in IL23A signaling. Signal transduction analysis confirms that this protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. Alternative splicing results in six spliced isoforms of IL-23R. Reports suggest that IL-23R plays an important role in psoriasis pathogenesis and is also a potential therapeutic target in inflammatory bowel disease.

Specifications

• Accession Number: IBD17; IL 23 R; IL-23 receptor; Il23r; IL-23 R; interleukin 23 receptor; interleukin 23 receptor-like; interleukin-23 receptor
• Assay Range: 0.2 to 50 ng/mL
• Assay Sensitivity: 0.2 ng/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 149233
• Gene Symbol: Il23r
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Storage Requirements: 2°C to 8°C
• Target: IL23R
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov