Invitrogen™ Human IL-27 R alpha ELISA Kit

Catalog No.	Quantity
EH272RBX5	5 x 96 Tests
EH272RB	96 Tests

Catalog No. EH272RBX5 Supplier Invitrogen™ Supplier No. EH272RBX5

Description

ELISA

Human IL-27 R alpha quantitates human IL-27 R alpha in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-27 R alpha.

In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells and type 2 (Th2) cells, which are critical for cell-mediated immunity and most antibody responses, respectively. The differentiation of Th1 cells is predominantly under the influence of IL12, while IL4 influences the differentiation of Th2 cells. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but not absent, Th1 or Th2 immune responses. The gene discussed here encodes a protein that is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level and is predicted to be a glycosylated transmembrane protein. Diseases associated with IL27RA include Hyper Ige Recurrent Infection Syndrome 4 and Crisponi/Cold-Induced Sweating Syndrome 2.

Specifications

• Accession Number: class I cytokine receptor; CRL1; CRL1IL-27 R; cytokine receptor family, class 1 (WSXWS), member 1; cytokine receptor WSX-1; Cytokine receptor-like 1; il-27 receptor; IL-27 receptor subunit alpha; IL27R; IL-27 R; IL-27 R subunit alpha; Il27ra; IL-27 RA; IL-27 R-alpha; interleukin 27 receptor subunit alpha; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; T cell cytokine receptor; T cell cytokine receptor; cytokine receptor family, class 1 (WSXWS), member 1; Tccr; T-cell cytokine receptor type 1; Type I T-cell cytokine receptor; UNQ296/PRO336; Ws x 1; WSX-1; ZcytoR1
• Assay Range: 0.85 to 200 ng/mL
• Assay Sensitivity: 0.85 ng/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 9466
• Gene Symbol: Il27ra
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Storage Requirements: 2°C to 8°C
• Target: TCCR
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins