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Gibco™ Human IL-34 Recombinant Protein, PeproTech®

Catalog No. p-7246240
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100 μg
2 μg
2 x 500 μg
250 μg
50 μg
500 μg
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Catalog No. 20034100UG

Supplier: Gibco™ 20034100UG

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Description

Recombinant Protein

200-34-1MG will be provided as 2 x 500 μg (200-34-500UG). Recombinant Human IL-34 is a 52.5 kDa homodimeric glycoprotein consisting of 460 amino acid residues, including a C-terminal His-Tag. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q6ZMJ4
For Use With (Application) Control, Bioactivity
Formulation Protein with no preservative
Gene ID (Entrez) 146433
Molecular Weight (g/mol) 52.5 kDa
Name Human IL-34
Purification Method Purified
Quantity 100 μg
Source HEK293 cells
Storage Requirements -20°C
Regulatory Status RUO
Endotoxin Concentration <1 EU/μg
Gene Alias 2010004A03Rik; AI593503; C16orf77; IL34; IL-34; ILN; Interleukin; interleukin 34; Interleukin34; interleukin-34
Common Name IL-34
Gene Symbol Il34
Biological Activity Measured by its ability to induce secretion of MCP-1 from PBMCs.
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Protein Tag His-tag
Sequence NEPLEMWPLT QNEECTVTGF LRDKLQYRSR LQYMKHYFPI NYKISVPYEG VFRIANVTRL QRAQVSEREL RYLWVLVSLS ATESVQDVLL EGHPSWKYLQ EVETLLLNVQ QGLTDVEVSP KVESVLSLLN APGPNLKLVR PKALLDNCFR VMELLYCSCC KQSSVLNWQD CEVPSPQSCS PEPSLQYAAT QLYPPPPWSP SSPPHSTGSV RPVRAQGEGL LPHHHHHHHH
Content And Storage -20°C
Activity Measured by its ability to induce secretion of MCP-1 from PBMCs.
Expression System HEK293 cells
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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