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  4. Gibco™ Human IL-36 beta (IL-1F8) Recombinant Protein, PeproTech® 

Gibco™ Human IL-36 beta (IL-1F8) Recombinant Protein, PeproTech®

Catalog No. 20036B100UG
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Catalog No. Quantity
20036B100UG 100 μg
200-36B-1MG 1 mg
20036B250UG 250 μg
200-36B-2UG 2 μg
20036B500UG 500 μg
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Catalog No. 20036B100UG Supplier Gibco™ Supplier No. 20036B100UG
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Description

Recombinant Protein

Recombinant Human IL-36beta is a 17.3 kDa protein containing 154 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

IL-36B is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. IL-36B is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP. Like the related proteins IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown. The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9NZH7
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 27177
Molecular Weight (g/mol) 17.3 kDa
Name Human IL-36 beta (IL-1F8)
Quantity 100 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias 2310043N20Rik; family of interleukin 1-eta; FIL1; FIL1 eta; FIL1-(ETA); Fil1e; FIL1H; FILI-(ETA); IL-1 eta; IL1-ETA; IL1F8; IL-1F8; IL1F8 (Canonical product IL-1F8a); IL-1F8 (FIL1-eta); IL1H2; IL-1H2; Il36b; Interleukin; interleukin 1 family, member 8; interleukin 1 family, member 8 (eta); interleukin 1, eta; interleukin 36, beta; interleukin-1 eta; Interleukin-1 family member 8; interleukin-1 homolog 2; Interleukin-1 Superfamily e; interleukin-36 beta
Common Name IL36B
Gene Symbol IL36B
Biological Activity Measured by its ability to induce IL-8 production by human PBMCs.
Conjugate Unconjugated
Recombinant Recombinant
Sequence MREAAPKSYA IRDSRQMVWV LSGNSLIAAP LSRSIKPVTL HLIACRDTEF SDKEKGNMVY LGIKGKDLCL FCAEIQGKPT LQLKEKNIMD LYVEKKAQKP FLFFHNKEGS TSVFQSVSYP GWFIATSTTS GQPIFLTKER GITNNTNFYL DSVE
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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