Invitrogen™ Human IL-4 Recombinant Protein

Catalog No.	Quantity
50-926-2	20 μg

Catalog No. 50-926-2 Supplier Invitrogen™ Supplier No. BMS337

Description

Recombinant Protein

Description: Interleukin-4 is a potent lymphoid cell growth factor, which stimulates the growth and survivability of certain B- cells and T- cells. Recombinant human IL-4 is a 15 kDa protein containing 130 amino acid residues. Purity: >98%. Molecular Weight: 15.0 kDa.

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.

Specifications

• Accession Number: P05112
• For Use With (Application): Neutralization
• Formulation: Protein with no preservative
• Gene ID (Entrez): 3565
• Molecular Weight (g/mol): 15 kDa
• Name: Human IL-4
• Purification Method: Purified
• Quantity: 20 μg
• Source: E. coli
• Storage Requirements: -20°C
• Regulatory Status: RUO
• Gene Alias: B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra
• Common Name: IL-4
• Gene Symbol: Il4
• Product Type: Protein
• Conjugate: Unconjugated
• Species: E. coli
• Recombinant: Recombinant
• Sequence: Human IL-4 recombinant protein contains 130 amino acids
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Protein Subtype: Recombinant
• Purity or Quality Grade: >98%

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov