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Brainxell Inc Spinal Astrocytes (Human iPSC-Derived, Male Line, 2M)
Supplier: Brainxell Inc BX0650302M
Spinal astrocytes derived from iPSC line WC-30, male. Contents: 1 vial of ≥2x10^6 viable cryopreserved cells. Marker Expression and Morphology: Spinal Astrocytes (BX-0650) express key astrocyte markers GFAP (green) at >80% and exhibit mature process-bearing morphologies (shown here with a DAPI stain). Labelling by the spinal-specific marker HOXB4 (red) with a Hoescht stain highlights the regional specificity of the Spinal Astrocytes. Function: Spinal Astrocytes promote mature motor neuron activity. Co-culturing motor neurons with spinal astrocytes promotes maximal calcium influx within 10 days. Co-culture spinal astrocytes with motor neurons also accelerates the development of activity recorded by multi-electrode array. Related diseases: Amyotrophic Lateral Sclerosis (ALS), Spinal muscular atrophy (SMA), & Spinal Cord Injury.
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