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Description
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq]
Specifications
Specifications
| For Use With (Application) | SDS-PAGE, Western Blot |
| Formulation | No additive |
| Gene ID (Entrez) | 354 |
| Molecular Weight (g/mol) | 30kDa |
| Name | KLK3 (Human) Native Protein |
| Preparation Method | Native protein purified from human seminal plasma |
| Purification Method | Gel filtration/Ion exchange chromatography purification |
| Quantity | 100 μg |
| Storage Requirements | Store at -20°C on dry atmosphere. After reconstitution with deionized water, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Regulatory Status | RUO |
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