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Invitrogen™ Human KPNA4 (aa 47-78) Control Fragment Recombinant Protein

Catalog No. RP102979
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RP102979 100 μL
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Catalog No. RP102979 Supplier Invitrogen™ Supplier No. RP102979
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83776. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O00629
Concentration ≥5.0 mg/mL
For Use With (Application) Neutralization, Control
Formulation PBS, 1M urea with no preservative; pH 7.4
Gene ID (Entrez) 3840
Name Human KPNA4 (aa 47-78) Control Fragment
pH Range 7.4
Purification Method Purified
Quantity 100 μL
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias 1110058D08Rik; importin; Importin alpha Q1; importin subunit alpha-3; importin subunit alpha-4; importin-alpha-Q1; IPOA3; karyopherin (importin) alpha 4; karyopherin alpha 4; karyopherin alpha 4 (importin alpha 3); karyopherin subunit alpha 4; karyopherin subunit alpha-4; KPNA4; MGC12217; MGC26703; predicted role in nuclear import; qip1; Qip1 protein; SRP3
Common Name KPNA4
Gene Symbol KPNA4
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence KRRNVPHEDICEDSDIDGDYRVQNTSLEAIVQ
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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