Invitrogen™ Human Kynureninase ELISA Kit

Catalog No.
EH289RBX10	10 x 96 Tests; HRP

Catalog No. EH289RBX10 Supplier Invitrogen™ Supplier No. EH289RBX10

Description

ELISA

Human Kynureninase quantitates human Kynureninase in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Kynureninase.

Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene. Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Accession Number: Q16719
• Assay Range: 0.61-150 ng/mL
• Assay Sensitivity: 0.61 ng/mL
• Conjugate: HRP
• Immunoassay Kit Format: Sandwich ELISA Kit
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• Target Species: Human
• For Use With (Equipment): Absorbance Microplate Reader
• Gene Alias: 4432411A05Rik; HAMAP-Rule:MF_03017}; KYNU; kynureninase; kynureninase (L-kynurenine hydrolase); kynureninase {ECO:0000255; kynureninase-like protein; KYNUU; L-kynurenine hydrolase; L-kynurenine hydrolase {ECO:00002554432411A05Rik; HAMAP-Rule:MF_03017}; KYNU; kynureninase; kynureninase (L-kynurenine hydrolase); kynureninase {ECO:0000255; kynureninase-like protein; KYNUU; L-kynurenine hydrolase; L-kynurenine hydrolase {ECO:0000255;
• Gene ID (Entrez): 8942
• Gene Symbol: Kynu
• Interassay CV: <12%
• Intraassay CV: <10%
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: Biotin
• Quantity: 10 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Shipping Condition: Wet or Dry Ice
• Storage Requirements: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
• Target: KYNU
• Test Time: 1 hr 20 min
• Total Assay Time: 4 hr 45 min