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  5. Invitrogen™ Human LAP/TGFb ProQuantum Immunoassay Kit  

Invitrogen™ Human LAP/TGFb ProQuantum Immunoassay Kit

Catalog No. A457305
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A45730 96 Tests
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Catalog No. A457305 Supplier Invitrogen™ Supplier No. A457305
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Description

ELISA

TGF beta-1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues. Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its prodomain. Activation of TGF-b1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins. Latent forms are complexes of TGF-beta, an aminoterminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P01137
Assay Range 16-250000 pg/mL
Assay Sensitivity <15 pg/mL
Conjugate FAM
Immunoassay Kit Format Proximity-based Immunoassay
Product Type ProQuantum
Sample Type Plasma, Serum, Supernatant
Target Species Human
For Use With (Equipment) qPCR Instruments
Gene Alias CED; DPD1; LAP; latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGFB; Tgfb1; Tgfb-1; TGFbeta; TGF-beta 1; TGFbeta1; TGF-beta1; TGF-beta-1; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor, beta 1; transforming growth factor-beta 1CED; DPD1; LAP; latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGFB; Tgfb1; Tgfb-1; TGFbeta; TGF-beta 1; TGFbeta1; TGF-beta1; TGF-beta-1; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor, beta 1; transforming growth factor-beta 1;
Gene ID (Entrez) 7040
Gene Symbol TGFB1
Kit Contents Assay Dilution Buffer, Antibody-Conjugate A, Antibody-Conjugate B, Antibody-Conjugate Dilution Buffer, Standard, Master Mix, Ligase, Antibody-Conjugate A, Antibody-Conjugate B, Antibody-Conjugate Dilution Buffer, Standard, Master Mix, Ligase
Label or Dye FAM™
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 2-5 μL, Serum 2-5 μL, Supernatant 2-5 μL
Shipping Condition Dry Ice
Storage Requirements -20°C
Target LAP
Test Time 30 min
Total Assay Time 2 hr
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