Invitrogen™ Human LAPTM4B (aa 217-242) Control Fragment Recombinant Protein

Catalog No.	Quantity
RP107657	100 μL

Catalog No. RP107657 Supplier Invitrogen™ Supplier No. RP107657

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67016. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

LAPTM4B is a multi-pass membrane protein. It belongs to the LAPTM4/LAPTM5 transporter family. LAPTM4b has active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma.

Specifications

• Accession Number: Q86VI4
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Neutralization, Control
• Formulation: PBS, 1M urea with no preservative; pH 7.4
• Gene ID (Entrez): 55353
• Name: Human LAPTM4B (aa 217-242) Control Fragment
• pH Range: 7.4
• Purification Method: Purified
• Quantity: 100 μL
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: C330023P13Rik; hypothetical protein 5; Laptm4b; LAPTM4beta; LC27; LOW QUALITY PROTEIN: lysosomal-associated transmembrane protein 4B; lysosomal associated protein transmembrane 4 beta; lysosomal protein transmembrane 4 beta; lysosomal-associated protein transmembrane 4B; lysosomal-associated transmembrane protein 4; lysosomal-associated transmembrane protein 4B; Lysosomal-associated transmembrane protein 4B-like protein; lysosome-associated transmembrane protein 4-beta; PSEC0001
• Common Name: LAPTM4B
• Gene Symbol: LAPTM4B
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: PNSIQEYIRQLPPNFPYRDDVMSVNP
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining