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Description
A positive reactivity in plasma B-cells is indicated by cytoplasmic staining. In lymphoid tissue, the normal kappa-to-lambda ratio is roughly 2:1, an indication for monoclonality is given if the kappa-to-lambda ratio is greater than 3:1 or less than 0.3:1. Visualization of signals should be performed at least at 100-fold magnification resulting in easily visible signals. Do not evaluate areas of necrosis, overlapping nuclei, over-digested nuclei, and nuclei with weak signal intensity.
Specifications
Specifications
| Content And Storage | Ready-to-use. No reconstitution, mixing, or dilution required. Bring to room temperature and mix briefly before use. Used in conjunction with Human Ig-kappa CISH Probe |
| For Use With (Application) | CISH-P |
| Includes | Reagent Provided: Digoxigenin-labeled oligonucleotides targeting mRNA sequences encoding Ig-lambda light chain constant regions. |
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