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Proteintech Group Inc Human LRRC32 ELISA Kit 96well

Supplier: Proteintech Group Inc KE0011996T
LRRC32, also known as GARP, is a transmembrane protein of 662 amino acids, the extracellular portion of which contains 20 leucine-rich repeats. LRRC32 is a cell surface receptor on regulatory T-lymphocytes (Treg cells), platelets, hepatic stellate cells and certain cancer cells. It has been demonstrated as a Treg-specific activation marker. LRRC32 is critical for the surface expression of latent TGF-β by binding to the complex and functioning as its cell surface receptor. Membrane bound LRRC32 can be shed from cell surface and exists in soluble form.
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