Invitrogen™ Human LRRC4 ELISA Kit

Catalog No.	Quantity
EH307RBX5	5 x 96 Tests
EH307RBX10	10 x 96 Tests
EH307RB	96 Tests

Catalog No. EH307RBX5 Supplier Invitrogen™ Supplier No. EH307RBX5

Description

ELISA

Human LRRC4 quantitates human LRRC4 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human LRRC4.

The LRRC4 gene, also known as netrin-G ligand 2 (NGL-2), is a brain-specific member of the leucine-rich repeat superfamily, playing a critical role in the central nervous system. Its expression is particularly high in areas such as the hippocampal CA1 and CA2 regions, as well as in granule cells of the dentate gyrus. LRRC4 is a known tumor suppressor gene associated with glioma suppression, as it regulates glioma cell growth, angiogenesis, and invasion through extensive signaling networks. It can participate in multiphase loops involving miRNA, transcription factors, and gene methylation modifications. This gene targets various genes involved in cell motility, impacting glioblastoma cell movement and polarization by binding to enhancer elements and activating transcription, notably the RAP1GAP gene. Its function and expression are crucial in maintaining normal brain function and hold potential implications in the management of gliomagenesis.

Specifications

• Accession Number: Q9HBW1
• Assay Range: 0.42-100 ng/mL
• Assay Sensitivity: 0.42 ng/mL
• Conjugate: HRP
• Immunoassay Kit Format: Sandwich ELISA Kit
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• Target Species: Human
• For Use With (Equipment): Absorbance Microplate Reader
• Gene Alias: BAG; brain tumor associated protein LRRC4; brain tumor-associated protein BAG; Brain tumor-associated protein MBAG1; leucine rich repeat containing 4; leucine rich repeat containing 4 protein; leucine-rich repeat-containing 4; leucine-rich repeat-containing protein 4; LIBG-like protein; LRRC4; LRRC4-like protein; MBAG1; NAG14; Nasopharyngeal carcinoma-associated gene 14 protein; netrin-G2 ligand; NGL-2; NLG2; NLG-2; protein NGL-2; UNQ554/PRO1111BAG; brain tumor associated protein LRRC4; brain tumor-associated protein BAG; Brain tumor-associated protein MBAG1; leucine rich repeat containing 4; leucine rich repeat containing 4 protein; leucine-rich repeat-containing 4; leucine-rich repeat-containing protein 4; LIBG-like protein; LRRC4; LRRC4-like protein; MBAG1; NAG14; Nasopharyngeal carcinoma-associated gene 14 protein; netrin-G2 ligand; NGL-2; NLG2; NLG-2; protein NGL-2; UNQ554/PRO1111;
• Gene ID (Entrez): 64101
• Gene Symbol: Lrrc4
• Interassay CV: <12%
• Intraassay CV: <10%
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: Biotin
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Shipping Condition: Wet or Dry Ice
• Storage Requirements: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
• Target: LRRC4
• Test Time: 1 hr 20 min
• Total Assay Time: 4 hr 45 min