Invitrogen™ Human MD-1 Synthetic Peptide

Catalog No.	Quantity
PEP0376	50 μg

Catalog No. PEP0376 Supplier Invitrogen™ Supplier No. PEP0376

Description

Synthetic Peptide

This peptide corresponds to 15 amino acids near the center of human MD-1. PEP-0376 can be used as a blocking peptide with polyclonal antibody PA5-20261.

MD-1, also known as LY86, is a glycoprotein involved in innate immunity. It is a component of the RP105/MD-1 complex, which is expressed primarily in immune cells like B-cells. MD-1 is structurally similar to MD-2, sharing only 16% sequence identity, yet both are implicated in lipopolysaccharide recognition. The protein contains the ML (MD-2-related lipid-recognition) domain, which is conserved across various species and mediates diverse biological functions by interacting with specific lipids. Structurally, MD-1 is characterized by a beta-rich fold consisting of multiple strands, which is integral to its biological activities. Though MD-1 mainly associates with RP105, its role in lipid recognition suggests functional similarities with proteins such as GM2A and NPC2, implying participation in broader immune signaling pathways.

Specifications

• Gene ID (Entrez): 9450
• Species: Human
• Purification Method: purified
• Accession Number: O95711
• Common Name: MD-1
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: dJ80N2.1; Ly86; Ly-86; Lymphocyte antigen 86; MD1; MD-1; MD-1, RP105-associated; MMD-1; Protein MD-1; RP1-80N2.1
• Gene Symbol: LY86
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS

Safety and Handling

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