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Gibco™ Human Midkine (MK) Recombinant Protein

Catalog No. PHC7084
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PHC7084 20 μg
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Description

Recombinant Protein

Carrier-Free Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. This lyophilized protein should be reconstituted in sterile, distilled water to a concentration of 0.1-1 mg/mL. Do not vortex. This solution can be stored at 2°C to 8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein, such as 0.1% BSA and store in working aliquots at -20°C to -80°C.

Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angiogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P21741
For Use With (Application) Bioactivity
Formulation PBS with no preservative
Gene ID (Entrez) 4192
Molecular Weight (g/mol) 13.4 kDa
Name Human Midkine (MK)
Purification Method Purified
Quantity 20 μg
Storage Requirements -20°C
Regulatory Status RUO
Endotoxin Concentration <0.1 ng/μg
Gene Alias amphiregulin-associated protein; ARAP; FLJ27379; MDK; Mek; Midgestation and kidney protein; midkine; midkine (neurite growth-promoting factor 2); MK; MK1; NEGF2; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein; Retanoic acid-responsive protein; retinoic acid inducible factor; retinoic acid-induced differentiation factor; retinoic acid-responsive protein
Common Name Midkine
Gene Symbol Mdk
Biological Activity ED50 = 0.1 - 10 ng/mL; determined by the dose-dependent chemotaxis of human neutrophils.
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Sequence Human Midkine recombinant protein contains 123 amino acids
Content And Storage -20°C
Classification Carrier-Free
Activity ED50 = 0.1 - 10 ng/mL; determined by the dose-dependent chemotaxis of human neutrophils.
Endotoxin Level <0.1 ng/μg
Shipping Condition Approved for shipment on Wet or Dry Ice
Expression System E. coli
Protein Family Chemokines & Receptors
Protein Form Recombinant, Ligand
Form Lyophilized
Protein Subtype Other Proteins
Research Category Neurobiology, Oncology, Stem Cell Research, Cardiovascular Research, Differentiation, Angiogenesis
Product Line Gibco
Purity or Quality Grade >98% by SDS-PAGE
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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