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Invitrogen™ Human MMP-14 ELISA Kit

Catalog No. EEL068
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96 Tests
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EEL068 96 Tests
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Catalog No. EEL068 Supplier Invitrogen™ Supplier No. EEL068
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ELISA

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P50281
Assay Range 0.63 to 40 ng/mL
Assay Sensitivity 0.38 ng/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 4323
Gene Symbol MMP14
Interassay CV <10%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Biotinylated Detection Antibody, HRP Conjugate, Standard & Sample Diluent, Biotinylated Detection Antibody Diluent, HRP Conjugate Diluent, Wash Buffer, TMB Substrate, Stop Solution, Plate Sealer
Label or Dye HRP
Quantity 96 Tests
Regulatory Status RUO
Sample Volume Plasma 100 μL, Serum 100 μL
Storage Requirements Refer to product documentation for component specific storage temperature.
Target MMP14
Test Time 1 hrs 20 mins
Total Assay Time 3 hrs 30 mins
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