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ACROBiosystems Biotinylated Human Nectin-4 (32-153), His,Avitag (NE4-H82Ea) is expressed from human 293 cells (HEK293). It contains AA Gly 32 - Leu 153 (Accession # Q96NY8-1).

Supplier:  ACROBiosystems NE4H82EA25UG

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Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.

Catalog No. 50-223-1350


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