Invitrogen™ Human NMNAT-1 ELISA Kit

Catalog No.	Quantity
EH341RBX5	5 x 96 Tests
EH341RB	96 Tests

Catalog No. EH341RBX5 Supplier Invitrogen™ Supplier No. EH341RBX5

Description

ELISA

Human NMNAT-1 quantitates human NMNAT-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human NMNAT-1.

The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Specifications

• Accession Number: 2610529L11Rik; 5730441G13Rik; D4Cole1e; deamido-NAD(+) diphosphorylase; deamido-NAD(+) pyrophosphorylase; EC 2.7.7.1; EC 2.7.7.18; LCA9; NAD(+) diphosphorylase; NAD(+) pyrophosphorylase; NaMN adenylyltransferase 1; nicotinamide mononucleotide adenylyl transferase; nicotinamide mononucleotide adenylyl transferase 1; Nicotinamide mononucleotide adenylyltransferase 1; nicotinamide nucleotide adenylyltransferase 1; nicotinamide/nicotinate mononucleotide adenylyltransferase 1; nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1; nicotinamide-nucleotide adenylyltransferase 1; Nicotinate-nucleotide adenylyltransferase 1; NMN adenylyltransferase 1; NMN/NaMN adenylyltransferase 1; Nmnat; NMNAT1; NMNATPNAT1; PNAT1; PNAT-1; pyridine nucleotide adenylyltransferase 1
• Assay Range: 8.19 to 2,000 pg/mL
• Assay Sensitivity: 8 pg/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 64802
• Gene Symbol: NMNAT1
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Storage Requirements: 2°C to 8°C
• Target: NMNAT1
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins