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Gibco™ Human NT-3 Recombinant Protein

Catalog No. PHC7036
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PHC7036 10 μg
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Catalog No. PHC7036 Supplier Gibco™ Supplier No. PHC7036
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Description

Recombinant Protein

Carrier-Free Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute NT-3 in water, to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2°C to 8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein, such as 0.1% BSA and store in working aliquots at -20°C to -80°C. Storage: The lyophilized protein is stable at room temperature for 1 month, but should be kept at -20°C for long term storage. Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C. Avoid repeated freeze/thaw cycles.

The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P20783
For Use With (Application) Bioactivity
Formulation Protein with no preservative
Gene ID (Entrez) 4908
Name Human NT-3
Purification Method Purified
Quantity 10 μg
Storage Requirements -20°C
Regulatory Status RUO
Endotoxin Concentration <0.1 ng/μg
Gene Alias AI316846; AI835689; HDNF; Nerve growth factor 2; neurotrophic factor; neurotrophin 3; neurotrophin-3; neurotrophin-3 (HDNF/NT-3); NGF2; NGF-2; NT3; NT-3; NTF3; Ntf-3
Common Name NTF3
Gene Symbol Ntf3
Biological Activity ED50 = 20 - 50 ng/mL; determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain septal cultures.
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Sequence MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
Content And Storage -20°C
Activity ED50 = 20 - 50 ng/mL; determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain septal cultures.
Endotoxin Level <0.1 ng/μg
Shipping Condition Approved for shipment on Wet or Dry Ice
Expression System E. coli
Protein Family Growth Factors & Receptors
Protein Form Recombinant, Ligand
Form Lyophilized
Protein Subtype Neurotrophic Factors
Research Category Stem Cell Research, Differentiation
Product Line Gibco
Purity or Quality Grade ≥98% by SDS-PAGE and HPLC
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WARNING: Cancer - www.P65Warnings.ca.gov
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