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ACROBiosystems Biotinylated Human HLA-A*02:01 NY-ESO-1 (SLLMWITQC) Complex Protein (HL1-H82E6) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*0201) & SLLMWITQC & Ile 21 - Met 119 (B2M) (Accession # AAA59606.1 (HLA-A*020
Supplier: ACROBiosystems HL1H82E625UG
NY-ESO-1, which is also well-known as New York esophageal squamous cell carcinoma 1, is an efficient target for cancer immunotherapy. This antigen is a member of cancer-testis antigens (CTAs) and is highly expressed in various cancers, including melanoma, ovarian, cervical cancer, etc. Adoptive T cell therapy with HLA-A2 restricted NY-ESO-1 transduced CD8+ T cells has improved the clinical response rates and overall survival of treatment-refractory melanoma patients.
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