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R&D Systems™ Human Nyctalopin/NYX (NP_072089) VersaClone cDNA

Catalog No. RDC2702
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RDC2702 10 μg
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Description

This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.

  • Also known as: CLRP; NBM1; CSNB1; CSNB4; CSNB1A
  • NYX belongs to the small leucinerich proteoglycan (SLRP) family of proteins.
  • Defects in NYX are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB).
  • The role of other SLRP proteins suggests that mutations in NYX disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.
  • The insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
  • For reasearch use only. Not for use in humans.

Specifications

Gene hNYX
Accession Number NP_072089
Concentration 10 μg at 0.2 μg/μL
Formulation cDNA is provided in 10 mM Tris-Cl, pH 8.5
Insert Type 1459 bp
Gene ID (Entrez) 60506
Content And Storage Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species Human
Quantity 10 μg
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