Invitrogen™ Human P1NP ELISA Kit

Catalog No.
EEL203	96 Tests

Catalog No. EEL203 Supplier Invitrogen™ Supplier No. EEL203

Description

ELISA

Procollagen type I N-terminal propeptide (P1NP) is a specific marker of bone formation, reflecting the synthesis of type I collagen, which constitutes the major part of the bone matrix. P1NP is derived during the conversion of procollagen to collagen, produced by osteoblasts during bone formation. Its primary clinical application lies in the diagnosis and monitoring of metabolic bone diseases, particularly osteoporosis. In osteoporotic patients, P1NP levels can predict bone mineral density (BMD) responses to treatments like teriparatide and romosozumab. Low serum levels of P1NP are indicative of a high risk of BMD loss, providing a valuable tool for premenopausal women with systemic lupus erythematosus (SLE) and other conditions affecting bone health.

Specifications

• Accession Number: P02452
• Assay Range: 15.63 to 1000 pg/mL
• Assay Sensitivity: 9.38 pg/mL
• Conjugate: HRP
• Detection Method: Colorimetric
• Immunoassay Kit Format: ELISA Microplate (Dismountable)
• Product Type: ELISA
• Sample Type: Plasma, Serum
• Target Species: Human
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 1277
• Gene Symbol: COL1A1
• Interassay CV: <10
• Intraassay CV: <10
• Kit Contents: Micro ELISA Plate (Dismountable), Reference Standard, Concentrated Biotinylated Detection Ab(100x), Concentrated HRP Conjugate (100x), Reference Standard & Sample Diluent, Biotinylated Detection Ab Diluent, HRP Conjugate Diluent, Concentrated Wash Buffer(25x), Substrate Reagent, Stop Solution, Plate Sealer, Product Description, Certificate of Analysis
• Label or Dye: Biotin
• Quantity: 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma: 100 μL, Serum: 100 μL
• Storage Requirements: Refer to product documentation for component specific storage temperature.
• Target: Procollagen I N-Peptide
• Test Time: 1 hr. 20 min.
• Total Assay Time: 3 hr. 30 min.