Invitrogen™ Human PCBP4 Synthetic Peptide

Catalog No.	Quantity
PEP0479	50 μg

Catalog No. PEP0479 Supplier Invitrogen™ Supplier No. PEP0479

Description

Synthetic Peptide

This peptide corresponds to 17 amino acids near the carboxy terminus of human MCG10C PEP-0479 can be used as a blocking peptide with polyclonal antibody PA5-20359.

MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family also referred to as alpha-CPs, bind to RNA with specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements. Its overexpression in transfected cells results in the suppression of cell proliferation by inducing apoptosis and cell cycle arrest in G2-M. Decreased expression of one isoform of MCG10 has been observed in many forms of lung cancer, leading to speculation that MCG10 can act as a tumor suppressor. Multiple alternatively spliced isoforms of MCG10 have been identified.

Specifications

• Gene ID (Entrez): 57060
• Species: Human
• Purification Method: purified
• Accession Number: P57723
• Common Name: PCBP4
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: 1200003L19Rik; alpha CP-4; alpha-CP4; AlphaCP-4; alphaCP-4 protein; CBP; LIP4; LYST-interacting protein; MCG10; Pcbp4; poly(rC) binding protein 4; poly(rC)-binding protein 4; RNA binding protein MCG10
• Gene Symbol: PCBP4
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS