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ACROBiosystems ACROBiosystems Human PD-1 Protein, His tag (Nanoparticle)
Supplier: ACROBiosystems PD1H52H2100UG
Recombinant Protein;100UG;Human PD-1, His tag (Nanoparticle) (PD1-H52H2) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Gln 167 (Accession # Q15116-1).;Human PD-1 Protein, His tag (Nanoparticle) is designed and expressed as nanoparticles of approximately 25 nm diameter by displaying PD-1 ECD in native conformation. The nanoparticles each was coated with an average of 180 PD-1 ECD.
The nanoparticle technology allows directional and high-density display of human PD-1 on the surface of nanoparticles, thus greatly enhances the immune response in vivo to otherwise poorly immunogenic epitopes.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.1 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.;Immobilized Human PD-1, His tag (Nanoparticle) (Cat. No. PD1-H52H2) at 1 μg/mL (100 μL/well) can bind Nivolumab with a linear range of 0.2-2 ng/mL (QC tested).;Immobilized H
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