Invitrogen™ Human PD-L1 ELISA Kit

Catalog No.	Quantity
BMS2327TEN	10 x 96 Tests
BMS2327	96 Tests

Catalog No. BMS2327TEN Supplier Invitrogen™ Supplier No. BMS2327TEN

Description

ELISA

Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.

Specifications

• Accession Number: Q9NZQ7
• Assay Range: 4.69-300 pg/mL
• Assay Sensitivity: <0.6 pg/mL
• Conjugate: HRP
• Immunoassay Kit Format: Sandwich ELISA Kit
• Product Type: ELISA
• Sample Type: Cell Lysates, Plasma, Serum, Supernatant
• Target Species: Human
• For Use With (Equipment): Absorbance Microplate Reader
• Gene Alias: A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1;
• Gene ID (Entrez): 29126
• Gene Symbol: Cd274
• Interassay CV: 3.4%
• Intraassay CV: 2.1%
• Kit Contents: Pre-coated 96 well plate, Standard , Biotinylated Detection antibody , Sample Diluent, Assay Buffer concentrate , Wash Buffer concentrate , SAV-HRP, Chromogen, Stop Solution , Adhesive Plate Covers, Biotinylated Detection antibody Sample Diluent Assay Buffer concentrate Wash Buffer concentrate, SAV-HRP Chromogen Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 10 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Cell Lysate 50 μL, Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Shipping Condition: Wet Ice
• Storage Requirements: 2-8°C
• Target: PD-L1 (CD274)
• Test Time: 1 hr 20 min
• Total Assay Time: 4 hr