Invitrogen™ Human PEAR1 ELISA Kit

Description

ELISA

Human PEAR1 quantitates human PEAR1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human PEAR1.

Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated; the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbbeta3 antagonist that also inhibits platelet aggregation. Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.

Specifications

• Accession Number: 3110045G13Rik; hPEAR1; Jagged and Delta protein; Jedi; Jedi-1; Megf12; mPEAR1; multiple EGF-like domains protein 12; multiple EGF-like-domains 12; multiple epidermal growth factor-like domains protein 12; Pear1; platelet endothelial aggregation receptor 1; Protein Jedi; RGD1305653; RP11-107D16.3
• Assay Range: 0.45 to 100 ng/mL
• Assay Sensitivity: 0.45 ng/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 375033
• Gene Symbol: PEAR1
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Storage Requirements: 2°C to 8°C
• Target: PEAR1
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov