Invitrogen™ Human PEN2 Synthetic Peptide

Catalog No.	Quantity
PEP0426	50 μg

Catalog No. PEP0426 Supplier Invitrogen™ Supplier No. PEP0426

Description

Synthetic Peptide

This peptide corresponds to 13 amino acids near the carboxy terminus of human PEN2. PEP-0426 can be used as a blocking peptide with polyclonal antibody PA5-20301.

Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase.

Specifications

• Gene ID (Entrez): 55851
• Species: Human
• Purification Method: purified
• Accession Number: Q9NZ42
• Common Name: PEN2
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: 1700023M09Rik; gamma-secretase subunit PEN-2; hematopoietic stem/progenitor cells protein MDS033; liver regeneration-related protein LRRGT00140; LRRGT00140 mRNA; MDS033; MSTP064; Pen2; Pen-2; presenilin enhancer 2; presenilin enhancer 2 homolog; presenilin enhancer 2 homolog (C. elegans); presenilin enhancer gamma secretase subunit; presenilin enhancer gamma-secretase subunit; presenilin enhancer protein 2; presenilin enhancer, gamma-secretase subunit; Psenen; RGD1312037
• Gene Symbol: PSENEN
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov