Abnova™ Human PF4 (P02776, 70 amino acids) native Protein from human platelets

Description

Used for Func, SDS-PAGE

Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990 [PubMed 1695112]).[supplied by OMIM]

Specifications

• Accession Number: P02776
• For Use With (Application): Functional Assay, SDS-PAGE
• Formulation: Lyophilized from PBS, pH 7.4
• Gene ID (Entrez): 5196
• Molecular Weight (g/mol): 7.8kDa
• Name: Human PF4 (P02776, 70 amino acids) native Protein from human platelets
• Quantity: 20 μg
• Storage Requirements: Store at −20°C on dry atmosphere.After reconstitution with sterilized water, store at −20°C.Aliquot to avoid repeated freezing and thawing.
• Regulatory Status: RUO
• Gene Alias: CXCL4, MGC138298, SCYB4
• Common Name: PF4
• Gene Symbol: PF4
• Biological Activity: Binding of HIT-antibodies.
• Species: Human
• Protein Tag: Untagged
• Expression System: Native protein purified from human platelets
• Form: Lyophilized
• Purity or Quality Grade: ≥95% by SDS-PAGE and HPLC