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Gibco™ Human Plateable Hepatocytes, Induction Qualified
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Quantity:
1.5 mL vial
Description
These plateable cryopreserved human hepatocytes are inducible and suitable for use in experiments monitoring in vitro enzyme induction.
Cells per vial: 4-8 million
The potentials of known clinically relevant enzyme inducers represented by 3-methylcholanthrene (3-MC, a prototypical CYP1A enzyme inducer, 3μM), phenobarbital (PB, a prototypical CYP2B inducer, 1000μM) and rifampicin (RIF, a prototypical CYP3A enzyme inducer, 10μM) have been assessed to verify that each lot is inducible.
Get the Results You Need with GIBCO Hepatocytes
High quality hepatocytes, with high viabilities, in vivo-like enzyme expression levels, and proper cell morphology increase the ability to draw in vitro/in vivo correlations and make sound decisions regarding a compound's fate. Experienced technicians and proprietary isolation techniques combined with stringent release specifications ensure you receive the highest quality cryopreserved hepatocytes.
Each lot is tested for:
Phase I and II enzyme activities
Proper morphology
Viabilities generally >75%
Attachment efficiency
Monolayer formation and integrity
For research use only. Not intended for human or animal therapeutic or diagnostic use.
Related Links:
Learn more about our cryopreserved hepatocytes
Learn about our full line of hepatocytes
Cells per vial: 4-8 million
The potentials of known clinically relevant enzyme inducers represented by 3-methylcholanthrene (3-MC, a prototypical CYP1A enzyme inducer, 3μM), phenobarbital (PB, a prototypical CYP2B inducer, 1000μM) and rifampicin (RIF, a prototypical CYP3A enzyme inducer, 10μM) have been assessed to verify that each lot is inducible.
Get the Results You Need with GIBCO Hepatocytes
High quality hepatocytes, with high viabilities, in vivo-like enzyme expression levels, and proper cell morphology increase the ability to draw in vitro/in vivo correlations and make sound decisions regarding a compound's fate. Experienced technicians and proprietary isolation techniques combined with stringent release specifications ensure you receive the highest quality cryopreserved hepatocytes.
Each lot is tested for:
For research use only. Not intended for human or animal therapeutic or diagnostic use.
Related Links:
Learn more about our cryopreserved hepatocytes
Learn about our full line of hepatocytes
Specifications
Specifications
| Content And Storage | Store in a cryostorage dewar or -135°C freezer. |
| Cell Type | Hepatocytes |
| Culture Type | Mammalian Cell Culture |
| Form | Cryopreserved |
| Species | Human |
| Donor Source | Single Donor |
| No. of Cells | 4-8 x 10^6 |
| Product Line | Gibco™ |
| Product Type | Hepatocytes |
| Quantity | 1.5 mL vial |
For Research Use Only. Not for use in diagnostic procedures.
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