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Gibco™ Human Plateable Hepatocytes, Transporter Qualified Non-distribution product as customer accommodation. Available on GSA/VA Contract for Federal Government customers only.

Human Plateable Hepatocytes, Transporter Qualified

Manufacturer:  Gibco™ HMCPTS

Catalog No. HMCPTS


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Description

Description

Plateable cryopreserved human hepatocytes assessed for transporter function using uptake transporter assays at both 4°C and 37°C.

Cells per vial: 4-8 million

Hepatocyte cultures were incubated with radiolabeled taurocholate, digoxin, and estradiol 17β glucuronide (E2-17G), substrates of the uptake and efflux transporters NTCP and BSEP, OCT1 and MDR1, and OATPs and MRP2, respectively. Accumulation rates and biliary excretion index (BEI%) were calculated.

Get the Results You Need with GIBCO Hepatocytes
High quality hepatocytes, with high viabilities, in vivo-like enzyme expression levels, and proper cell morphology increase the ability to draw in vitro⁄in vivo correlations and make sound decisions regarding a compound's fate. Experienced technicians and proprietary isolation techniques combined with stringent release specifications ensure you receive the highest quality cryopreserved hepatocytes.

Each lot is tested for:
  • Phase I and II enzyme activities
  • Proper morphology
  • Viabilities generally >75%
  • Attachment efficiency
  • Monolayer formation and integrity

    For research use only. Not intended for human or animal therapeutic or diagnostic use.

    Related Links:

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    Learn about our full line of hepatocytes ,

    Note:
    These products require shipment in LN2 vapor dewars therefore additional fees may apply.

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  • Specifications

    Specifications

    Hepatocyte
    Single Donor
    Cryopreserved
    1 vial
    Gibco™
    4-8 x 106
    Human
    Hepatocytes
    Safety and Handling

    Safety and Handling

    SDS
    Documents
    Product Certifications
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    For Research Use Only. Not for use in diagnostic procedures.