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Gibco™ Human Plateable Hepatocytes, Uptake Qualified

Catalog No. HMCPUS
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HMCPUS 1.5 mL
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Description

Human Plateable Hepatocytes, Uptake Qualified

Cryopreserved human hepatocytes for use in transporter-mediated uptake applications.

Cells per vial: 4-8 million

Prototypical hepatic uptake transporter substrates taurocholate and estradiol-17β-glucuronide have been assessed to qualify the transport function of hepatic NTCP (SLC10A1) and OATP1B14/3 (SLCO1B1/3), respectively. The transport of each substrate (radiolabeled) was monitored by scintillation analysis and active transport values (37°C - 4°C) determined by linear regression.

Get the Results You Need with GIBCO™ Hepatocytes
High quality hepatocytes, with high viabilities, in vivo-like enzyme expression levels, and proper cell morphology increase the ability to draw in vitro/in vivo correlations and make sound decisions regarding a compound's fate. Experienced technicians and proprietary isolation techniques combined with stringent release specifications ensure you receive the highest quality cryopreserved hepatocytes.

Each lot is tested for:


  • Phase I and II enzyme activities
  • Proper morphology
  • Viabilities generally >75%
  • Attachment efficiency
  • Monolayer formation and integrity

    For research use only. Not intended for human or animal therapeutic or diagnostic use.

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    Learn more about our cryopreserved hepatocytes

    Learn about our full line of hepatocytes
    • TRUSTED_SUSTAINABILITY

    Specifications

    Cell Passage Number Passage 0
    Content And Storage Vials of cryopreserved hepatocytes should be stored in a cryostorage dewar or -135°C freezer.
    Cell Type Hepatocytes
    Culture Type Adherent Cell Culture
    Form Cryopreserved
    Species Human
    Donor Source Single Donor
    Format Tube
    No. of Cells 4-8 x 106
    Product Line Gibco
    Product Type Hepatocytes
    Quantity 1.5 mL
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    For Research Use Only. Not for use in diagnostic procedures.

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