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Gibco™ Human Plateable Hepatocytes, Uptake Qualified

Catalog No. HMCPUS
Encompass_Preferred
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Quantity:
1.5 mL

Human Plateable Hepatocytes, Uptake Qualified

Cryopreserved human hepatocytes for use in transporter-mediated uptake applications.

Cells per vial: 4-8 million

Prototypical hepatic uptake transporter substrates taurocholate and estradiol-17β-glucuronide have been assessed to qualify the transport function of hepatic NTCP (SLC10A1) and OATP1B14/3 (SLCO1B1/3), respectively. The transport of each substrate (radiolabeled) was monitored by scintillation analysis and active transport values (37°C - 4°C) determined by linear regression.

Get the Results You Need with GIBCO™ Hepatocytes
High quality hepatocytes, with high viabilities, in vivo-like enzyme expression levels, and proper cell morphology increase the ability to draw in vitro/in vivo correlations and make sound decisions regarding a compound's fate. Experienced technicians and proprietary isolation techniques combined with stringent release specifications ensure you receive the highest quality cryopreserved hepatocytes.

Each lot is tested for:


  • Phase I and II enzyme activities
  • Proper morphology
  • Viabilities generally >75%
  • Attachment efficiency
  • Monolayer formation and integrity

    For research use only. Not intended for human or animal therapeutic or diagnostic use.

    Related Link

    Learn more about our cryopreserved hepatocytes

    Learn about our full line of hepatocytes
  • TRUSTED_SUSTAINABILITY

    Specifications

    Cell Passage Number Passage 0
    Content And Storage Vials of cryopreserved hepatocytes should be stored in a cryostorage dewar or -135°C freezer.
    Cell Type Hepatocytes
    Culture Type Adherent Cell Culture
    Form Cryopreserved
    Species Human
    Donor Source Single Donor
    Format Tube
    No. of Cells 4-8 x 106
    Product Line Gibco™
    Product Type Hepatocytes
    Quantity 1.5 mL
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    For Research Use Only. Not for use in diagnostic procedures.

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