Abnova™ Human PLG native Protein from human plasma

Description

Used for Func, SDS-PAGE

Plasminogen (PLG) is a circulating zymogen that is converted to the active enzyme plasmin by cleavage of the peptide bond between arg560 and val561, which is mediated by urokinase (PLAU; MIM 191840) and tissue plasminogen activator (PLAT; MIM 173370). The main function of plasmin is to dissolve fibrin (see, e.g., FGA, MIM 134820) clots. Plasmin, like trypsin, belongs to the family of serine proteinases (Miyata et al., 1982 [PubMed 6216475]; Forsgren et al., 1987 [PubMed 3030813]).[supplied by OMIM]

Specifications

• Concentration: 4.1 mg/mL
• For Use With (Application): Functional Study, SDS-PAGE
• Formulation: In 0.1M Hepes, 0.1M NaCl, pH 7.4
• Gene ID (Entrez): 5340
• Molecular Weight (g/mol): 92kDa
• Name: PLG (Human) Native Protein
• Preparation Method: Native protein purified from human plasma
• Purification Method: Lysine sepharose chromatography
• Quantity: 1 mg
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Regulatory Status: RUO
• Gene Alias: DKFZp779M0222
• Common Name: PLG
• Gene Symbol: PLG
• Biological Activity: No plasmin activity is detected with chromogenic substrate S-2251.
  > 98% conversion to plasmin is observed upon activation with uPA.
• Species: Human
• Protein Tag: None
• Expression System: Native protein purified from human plasma
• Form: Liquid