Invitrogen™ Human Properdin ELISA Kit

Description

ELISA

Human Properdin quantitates human Properdin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Properdin.

This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.

Specifications

• Accession Number: BCFG; Bf; BFD; C3 Proaccelerator; C3/C5 convertase; cfb; Cfp; Complement factor P; complement factor properdin; GBG; H2-Bf; PBF2; PFC; PFD; PROPERDIN; properdin factor, complement; Properdin P factor, complement
• Assay Range: 42 to 10,000 pg/mL
• Assay Sensitivity: 42 pg/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 5199
• Gene Symbol: CFP
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Storage Requirements: 2°C to 8°C
• Target: Properdin
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins