Invitrogen™ Human PRTFDC1 Synthetic Peptide

Catalog No.	Quantity
PEP0713	50 μg

Catalog No. PEP0713 Supplier Invitrogen™ Supplier No. PEP0713

Description

Synthetic Peptide

This peptide corresponds to 14 amino acids near the center of human PRTFDC1 PEP-0713 can be used as a blocking peptide with polyclonal antibody PA5-20593.

Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.

Specifications

• Gene ID (Entrez): 56952
• Species: Human
• Purification Method: purified
• Accession Number: Q9NRG1
• Common Name: PRTFDC1
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: HHGP; phosphoribosyl transferase domain containing 1; phosphoribosyltransferase domain-containing protein 1; PRTFDC1
• Gene Symbol: PRTFDC1
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS