Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
STEMCELL Technologies Human Recombinant CNTF, Size: 10 ug
Supplier: STEMCELL Technologies 78010
Use ciliary neurotrophic factor (CNTF) to differentiate human pluripotent stem cell (hPSC)-derived neural progenitor cells into astrocytes (Krencik Zhang. Nat Protoc 2011). CNTF binds to its receptor CNFTRa and induces a heterodimer formation with the IL-6 receptor gp130 and LIF receptor (LIFR)- and activates the JAK/STAT ERK and the PI3K signaling cascades (Schuster et al. J Biol Chem 2003). CNTF plays an important role in neurogenesis and the differentiation of neural stem cells and has been suggested to possess a therapeutic role in treating neurological disorders (Ding et al. J Alzheimers Dis 2013.) CNTF also has been reported to protect oligodendrocytes from death induced by apoptosis (Louis et al.). Human recombinant CNTF from STEMCELL comes lyophilized with ≥ 95% purity specific activity EC50 200 ng/mL endotoxin levels verified 0.2 EU/μg protein. Alternative name Ciliary neurotrophic factor
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?