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STEMCELL Technologies Human Recombinant FGF-6, Size: 500 ug
Supplier: STEMCELL Technologies 78184.1
Fibroblast growth factor 6 (FGF-6) is a heparin-binding member of the FGF family regulators of cell proliferation differentiation and function. FGF-6 binds and signals through the FGF receptors 1c 2c and 4 (Ornitz et al.). FGF-6 is a potent mitogen for fibroblasts vascular endothelial cells and prostate carcinoma cells (Asada et al. Pizette et al. Ropiquet et al.). FGF-6 is primarily expressed in epithelial and mesenchymal cell lineages. During development FGF-6 is expressed in skeletal muscle consistent with its role in muscle differentiation and regeneration (Floss et al.). FGF-6 has also been shown to promote chondrogenesis in embryonic somites in conjunction with transforming growth factor beta 2 (TGF-2 Grass et al.).
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