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STEMCELL Technologies Human Recombinant Flt3/Flk-2 Ligand, ACF, Size: 1000 ug
Supplier: STEMCELL Technologies 78137.2
Modulate the proliferation differentiation and survival of hematopoietic stem and progenitor cells with Flt3/Flk-2 Ligand (Hannum et al. Nature 1994). Flt3/Flk-2 Ligand in combination with stem cell factor and thrombopoietin can promote the expansion of primitive CD34 hematopoietic cells (Hannum et al.). Together with different interleukins and cytokines Flt3/Flk-2 Ligand can also regulate the development of various lymphoid progenitor cells including dendritic cell B cell T cell and NK cell progenitors. Flt3/Flk-2 Ligand is produced by a variety of cell types but expression of its receptor is restricted to CD34 hematopoietic stem and progenitor cells (Drexler Quentmeier. Growth Factors 2004). Human recombinant Flt3/Flk-2 Ligand from STEMCELL is animal component-free and comes lyophilized with ≥ 95% purity specific activity EC50 10 ng/mL endotoxin levels verified 1 EU/μg protein. Alternative names
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