Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
STEMCELL Technologies Human Recombinant Fractalkine (CX3CL1), Size: 25 µg
Supplier: STEMCELL Technologies 78051.1
Mediate cell migration and adhesion with fractalkine (White & Greaves. Arterioscler Thromb Vasc Biol, 2012). Fractalkine (CX3CL1) is characterized by a C-X3-C cysteine motif within the chemokine domain (Bazan et al. Nature, 1997). The chemokine domain is connected to a mucin-like stalk, followed by a transmembrane region and a C-terminal intracellular domain (Jones et al. Mol Interv, 2010). Cleavage at the base of the stalk generates a soluble chemokine, which acts as a chemoattractant of target cells (Apostolakis & Spandidos. Acta Pharmacol Sin, 2013). The protein signals through interaction with CX3CR1, which is expressed on monocytes, NK cells, T cells, microglia, and smooth muscle cells. Human recombinant fractalkine from STEMCELL comes lyophilized with ≥ 95% purity; EC50 ≤ 1.5 μg/mL; endotoxin levels verified ≤ 0.2 EU/μg protein. Alternative names: C3Xkine, Chemokine (C-X3-C motif) ligand 1, FKN, Neurotactin, NTN, NTT, SCYD1, Small inducible cytokine subfamily D member 1.
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?