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STEMCELL Technologies Human/Mouse Recombinant NT-3, Size: 100 µg
SDP

Supplier:  STEMCELL Technologies 78074.1

Encompass

Use neurotrophin-3 (NT-3) to generate β-tubulin III+ peripheral neurons from neural crest stem cells (Menendez et al. Nat Protoc, 2013) and oligodendrocyte precursor cells from human embryonic stem (ES) and induced pluripotent stem (iPS) cells (Douvaras et al. Stem cell reports, 2014). NT-3 is a member of the nerve growth factor (NGF) family of proteins that includes neuron growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-4/5. NT-3 signals a number of trophic effects through its transducing receptor tyrosine kinase TrkC and is known to promote the survival, development, and differentiation of neurons (Chalazonitis. Mol Neurobiol, 1996). Human/mouse recombinant NT-3 from STEMCELL comes lyophilized with ≥ 95% purity; specific activity EC50 ≤ 20 ng/mL (for Lot #1000050644 or higher) and EC50 ≤ 20 μg/mL (for other lots); endotoxin levels verified ≤ 1 EU/μg protein. Alternative names: HGNF, NGF-2, Nerve growth factor 2, Neurotrophin 3, NT3.

Catalog No. 50-197-6411


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