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Invitrogen™ Human Relaxin-1 ELISA Kit

Catalog No. EH391RBX5
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ELISA

Human Relaxin-1 quantitates human Relaxin-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Relaxin-1.

Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds; however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number bA12D24.3.1; bA12D24.3.2; H1; H1RLX; preprorelaxin; preprorelaxin H1; prorelaxin 1; Prorelaxin H1; RELAX; relaxin 1; Relaxin 1 (H1); Relaxin A chain; Relaxin B chain; relaxin RLXH1; Rln; RLN1; rlx; RLX bA12D24.3.1; RLXH1
Assay Range 0.23 to 50 ng/mL
Assay Sensitivity 0.23 ng/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 6013
Gene Symbol Rln1
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target Relaxin 1
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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