Invitrogen™ Human Relaxin-1 ELISA Kit

Catalog No.	Quantity
EH391RBX10	10 x 96 Tests

Catalog No. EH391RBX10 Supplier Invitrogen™ Supplier No. EH391RBX10

Description

ELISA

Human Relaxin-1 quantitates human Relaxin-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Relaxin-1.

Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds; however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet.

Specifications

• Accession Number: P04808
• Assay Range: 0.23-50 ng/mL
• Assay Sensitivity: 0.23 ng/mL
• Conjugate: HRP
• Immunoassay Kit Format: Sandwich ELISA Kit
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• Target Species: Human
• For Use With (Equipment): Absorbance Microplate Reader
• Gene Alias: bA12D24.3.1; bA12D24.3.2; H1; H1RLX; preprorelaxin; preprorelaxin H1; prorelaxin 1; Prorelaxin H1; RELAX; relaxin 1; Relaxin 1 (H1); Relaxin A chain; Relaxin B chain; relaxin RLXH1; Rln; Rln1; rlx; RLX bA12D24.3.1; RLXH1bA12D24.3.1; bA12D24.3.2; H1; H1RLX; preprorelaxin; preprorelaxin H1; prorelaxin 1; Prorelaxin H1; RELAX; relaxin 1; Relaxin 1 (H1); Relaxin A chain; Relaxin B chain; relaxin RLXH1; Rln; Rln1; rlx; RLX bA12D24.3.1; RLXH1;
• Gene ID (Entrez): 6013
• Gene Symbol: Rln1
• Interassay CV: <12%
• Intraassay CV: <10%
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: Biotin
• Quantity: 10 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Shipping Condition: Wet or Dry Ice
• Storage Requirements: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
• Target: Relaxin 1
• Test Time: 1 hr 20 min
• Total Assay Time: 4 hr 45 min