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Invitrogen™ Human RNASE3 ELISA Kit

Catalog No. EEL208
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96 Tests
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Catalog No.
EEL208 96 Tests
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Catalog No. EEL208 Supplier Invitrogen™ Supplier No. EEL208
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Description

ELISA

ECP (eosinophil cationic protein), also known as RNS3 or RNASE3 (ribonuclease, RNase A family, 3), is a 160 amino acid potent cytotoxic secretory protein that belongs to the pancreatic ribonuclease family. ECP localizes to the granule matrix of the eosinophil and is involved in the immune response system. ECP is a cytotoxin, neurotoxin and helminthotoxin that is secreted by activated human eosinophils. ECP exhibits anti-parasitic, antibacterial and ribonucleolytic activities. It has been suggested that ECP induces the neurotoxic effect known as the Gordon phenomenon, a syndrome manifested by ataxia, muscular rigidity, paralysis and tremor that may lead to death. ECP is considered a marker of eosinophilic inflammation and high levels have been found in cases of active asthma and other allergic diseases.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P12724
Assay Range 39.06 to 2500 pg/mL
Assay Sensitivity 23.44 pg/mL
Conjugate HRP
Detection Method Colorimetric
Immunoassay Kit Format ELISA Microplate (Dismountable)
Product Type ELISA
Sample Type Plasma, Serum
Target Species Human
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 6037
Gene Symbol RNASE3
Interassay CV <10
Intraassay CV <10
Kit Contents Micro ELISA Plate (Dismountable), Reference Standard, Concentrated Biotinylated Detection Ab(100x), Concentrated HRP Conjugate (100x), Reference Standard & Sample Diluent, Biotinylated Detection Ab Diluent, HRP Conjugate Diluent, Concentrated Wash Buffer(25x), Substrate Reagent, Stop Solution, Plate Sealer, Product Description, Certificate of Analysis
Label or Dye Biotin
Quantity 96 Tests
Regulatory Status RUO
Sample Volume Plasma: 100 μL, Serum: 100 μL
Storage Requirements Refer to product documentation for component specific storage temperature.
Target RNASE3
Test Time 1 hr. 20 min.
Total Assay Time 3 hr. 30 min.
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